Hellenistic Greeceby Julia
Main articles: Wars of Alexander the Great, Hellenistic Period, and Hellenistic civilization The Hellenistic period lasted from 323 BC, which marked the end of the Wars of Alexander the Great, to the annexation of the Greece by the Roman Republic in 146 BC. Although the establishment of Roman rule did not break the continuity of Hellenistic society and culture, which remained essentially unchanged until the advent of Christianity, it did mark the end of Greek political independence. During the Hellenistic period, the importance of "Greece proper" (that is, the territory of modern Greece) within the Greek-speaking world declined sharply. The great centers of Hellenistic culture were Alexandria and Antioch, capitals of Ptolemaic Egypt and Seleucid Syria respectively.
The conquests of Alexander had numerous consequences for the Greek city-states. It greatly widened the horizons of the Greeks and led to a steady emigration, particularly of the young and ambitious, to the new Greek empires in the east. Many Greeks migrated to Alexandria, Antioch and the many other new Hellenistic cities founded in Alexander's wake, as far away as what are now Afghanistan and Pakistan, where the Greco-Bactrian Kingdom and the Indo-Greek Kingdom survived until the end of the 1st century BC.
After the death of Alexander his empire was, after quite some conflict, divided amongst his generals, resulting in the Ptolemaic Kingdom (based upon Egypt), the Seleucid Empire (based on the Levant, Mesopotamia and Persia) and the Antigonid dynasty based in Macedon. In the intervening period, the poleis of Greece were able to wrest back some of their freedom, although still nominally subject to the Macedonian Kingdom. The city states formed themselves into two leagues; the Achaean League (including Thebes, Corinth and Argos) and the Aetolian League (including Sparta and Athens). For much of the period until the Roman conquest, these leagues were usually at war with each other, and/or allied to different sides in the conflicts between the Diadochi (the successor states to Alexander's empire).